Services

From Formulation Concept to Clinical Evaluation

Bakunova provides end-to-end formulation development and evaluation services for cosmetic actives and advanced skincare products. Using our proprietary Xnova™ technology platform, we develop optimized formulations designed to improve active-ingredient stability, solubility, skin delivery, bioavailability, safety, and performance.

Powered by XNOVA — Delivery Technology Services

Integrated formulation development, scientific evaluation and clinical validation.

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Xnova™ Technology Platform

Formulation Development

We develop customized formulations based on the physicochemical properties, biological activity, and intended application of each active ingredient.

Our formulation capabilities include:

Liposomes Microemulsions β-Cyclodextrin complexes Solid lipid nanoparticles Ionic-liquid delivery systems Microsponge technologies
XNOVA — Delivery Technology Services
01Active profiling
02Technology selection
03Formulation optimization
Scientific Evaluation Services

Characterize quality, biological activity, safety and clinical performance.

Each evaluation programme is aligned with the formulation, active ingredient, intended application, and product-development objective.

01Quality

Physicochemical Characterization

We evaluate the critical quality attributes of developed formulations to ensure stability, consistency, and product performance.

Our services include:

  • Particle size and size distribution
  • Zeta potential
  • Encapsulation efficiency
  • Active-ingredient content
  • Solubility and dissolution
  • pH, viscosity, and appearance
  • In vitro release studies
  • Permeation and skin-deposition studies
  • Accelerated and long-term stability studies
02In Vitro

In Vitro Biological Evaluation

Our cell-based studies assess the biological activity, safety, and efficacy of formulations before advancing to more complex testing.

Evaluation capabilities include:

  • Cytotoxicity and cell viability
  • Anti-inflammatory activity
  • Antioxidant activity
  • Collagen and elastin support
  • Anti-ageing activity
  • Melanogenesis and pigmentation studies
  • Antimicrobial and anti-acne activity
  • Cellular uptake and mechanism-of-action studies
03Ex Vivo

Ex Vivo Biological Evaluation

We use physiologically relevant skin models and biological tissues to understand formulation behaviour and performance under conditions that closely represent human skin.

Our ex vivo services include:

  • Skin penetration and permeation
  • Epidermal and dermal deposition
  • Barrier-function assessment
  • Histological evaluation
  • Biomarker analysis
  • Comparative product-performance studies
04Safety

Safety and Performance Evaluation

Each formulation is evaluated through a structured testing programme designed to establish product safety, functional performance, and suitability for its intended application.

Testing may include:

  • Skin irritation and sensitization
  • Phototoxicity assessment
  • Ocular irritation screening
  • Compatibility studies
  • Performance benchmarking
  • Reference-product comparison
05Clinical

Clinical Evaluation

Bakunova supports scientifically designed clinical studies to validate product safety, tolerability, and consumer-relevant benefits.

Clinical evaluation may include:

  • Dermatological safety assessment
  • Skin hydration and barrier improvement
  • Fine-line and wrinkle reduction
  • Skin firmness and elasticity
  • Pigmentation and skin-tone improvement
  • Acne and sebum-control assessment
  • Consumer-perception studies
End-to-End Development

Integrated Development Approach

From active-ingredient selection and formulation design to physicochemical characterization, biological testing, and clinical validation, Bakunova provides a complete development pathway for creating safe, stable, and high-performance cosmetic products.

ConceptFormulationEvaluationMarket readiness Transform your active ingredient into a scientifically validated, market-ready formulation with Bakunova.
Start Your Programme

From formulation concept to clinical evaluation.

Discuss your cosmetic active, formulation prototype, testing requirement, or clinical-development objective with Bakunova.

Discuss a project info@bakunova.com